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Bloodstream infections with Pseudomonas aeruginosa often occur in highly comorbid, immunocompromised patients with previous antimicrobial exposure, suggesting the need for longer treatment courses, but data on optimal duration are scarce. Bae and colleagues performed a 10-year retrospective study of 290 patients at a large medical center in Seoul, Korea, with uncomplicated P. aeruginosa bacteremia (defined as absence of widespread or deep-seated infection, with negative blood cultures documented within 48 hours of the index culture). The composite rate of death or recurrent infection within 30 days of ending treatment was compared between patients who received a short course (7–11 days; 97 patients) or long course (12–21 days; 193 patients)…