Racial/Ethnic Disparities in Patients Who Decline Thrombolysis for Stroke

After adjustments for patient- and facility-level factors, non-Hispanic Black patients declined tPA more often than non-Hispanic white patients.

Achieving health equity and optimal outcomes for acute ischemic stroke includes an evaluation of the factors at play when a patient meets eligibility criteria for treatment with tissue plasminogen activator (tPA) but declines treatment. Using nationwide data from the Get With The Guidelines–Stroke registry, investigators identified 177,115 patients with acute ischemic stroke who presented to participating centers between January 1, 2016, and March 28, 2019, within 4.5 hours of symptom onset and were otherwise eligible for tPA. Self-reported race/ethnicity was recorded as 68.9% non-Hispanic white, 16.4% non-Hispanic Black, 7.7% Hispanic (any race), 2.9% Asian, and 4.0% other or unable to determine.

Overall, 3.7% (6545) of these patients had “…

Reviewing Author

Anthony S. Kim, MD

Disclosures

Grant/Research SupportNIH/National Institute of Neurological Disorders and Stroke; NIH/National Center for Advancing Translational Sciences

Anthony S. Kim, MD

Disclosures

Grant/Research SupportNIH/National Institute of Neurological Disorders and Stroke; NIH/National Center for Advancing Translational Sciences

Racial/Ethnic Disparities in Patients Who Decline Thrombolysis for Stroke

Topics

Reviewing Author