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Mayo Clinic researchers recently published a retrospective analysis of nirmatrelvir/ritonavir (Paxlovid) treatment for COVID-19. The data on the rate of severe outcomes is reassuring, says Dr. Paul Sax in the latest HIV and ID Observations post, but it likely underestimates the rebound rate. Additionally, questions remain about whether treatment with subsequent rebound reduces — or increases — the time people are contagious,
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