Recurrent Infective Endocarditis in Those Who Inject Drugs

In a retrospective study, risk for endocarditis recurrence was associated with misuse of a peripherally inserted central venous catheter for outpatient treatment.

The incidence of infective endocarditis is rising among people who inject drugs, and recurrence in this group is substantial (estimated to be up to 25%). One risk factor, previously identified by these authors, is misuse of peripherally inserted central venous catheters. Now, a retrospective cohort analysis has been performed in hospitalized adult patients who injected drugs and had diagnoses of infective endocarditis from 2007 to 2018 at three hospitals in Ottawa, Ontario, Canada.

Among 310 subjects, 74 experienced recurrent endocarditis. Bivariate and multivariable competing-risks analysis revealed that factors associated with repeat episodes included misuse of a peripherally inserted central venous catheter (P=0.02), outpatient treatment …

Reviewing Author

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Recurrent Infective Endocarditis in Those Who Inject Drugs

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Reviewing Author