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Could broad population-based screening for cardiovascular disease — using an array of diagnostic tests — lower mortality? To find out, Danish investigators randomized about 47,000 men (age range, 65–74) selected from a national registry to a group invited to participate in comprehensive CVD screening or to a control group. Screening included coronary artery calcium scoring, computed tomography to identify aortic and iliac aneurysms, electrocardiography, ankle-brachial blood pressures, and glucose and lipid profile measurements. Positive results were provided to patients and their primary care physicians with recommendations for follow-up or referral as needed.
About two thirds of the invited group actually underwent screening. In an intentio…