Loading...
In adjuvant therapy trials of patients with resected colorectal liver metastases, recurrence-free survival (RFS) has been used as a surrogate for overall survival (OS), allowing for earlier interpretation of therapeutic outcomes. However, the correlation between RFS and OS in this disease setting has not been validated.
Now, investigators have conducted a retrospective, single-institution study spanning 30 years to evaluate the correlation between RFS and OS in 2983 patients who underwent curative hepatic resection for colorectal liver metastases. Nearly half of patients (46%) had left-sided primary tumors that were node-positive (62%), and most (63%) had one or two liver metastases resected that were synchronous with the primary cancer (56%…