How Does Single Maintenance and Reliever Therapy Fare in the Real World?

Once again, maintenance and reliever use of inhaled steroids/formoterol for asthma was superior to using albuterol as a rescue inhaler.

Both the National Asthma Education and Prevention Program (NEJM JW Gen Med Jan 15 2021 and JAMA 2020; 324:2301) and the Global Initiative for Asthma (GINA) guidelines recommend using single maintenance and reliever therapy (MART) for all patients with moderate-to-severe asthma. GINA goes a step further and states that albuterol should no longer be used and that inhaled corticosteroids (ICS) with formoterol in a single inhaler should be the reliever of choice. Although we have excellent randomized trials supporting use of MART, we have few “real-world” studies.

In a retrospective study from South Korea, researchers compared two groups: The MART group (231 adults) received ICS/formoterol twice daily for maintenance and used the same inhaler as…

Reviewing Author

David J. Amrol, MD

Disclosures

Speaker’s BureauAstraZeneca; Incyte

David J. Amrol, MD

Disclosures

Speaker’s BureauAstraZeneca; Incyte

How Does Single Maintenance and Reliever Therapy Fare in the Real World?

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Reviewing Author