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Cardiovascular health (CVH) has been associated with brain health. To explore this relationship further, investigators conducted a population-based cohort study that determined how global, behavioral, and biological CVH profiles as well as metabolic genetic risk factors are associated with MRI measures of vascular brain aging in 317 Swedish adults (age, ≥60 years; 62% women).
Favorable, intermediate, and unfavorable CVH profiles were determined at baseline by four behavioral factors (smoking, physical activity, dietary habits, and body-mass index) and three biological factors (total cholesterol, blood pressure, and fasting plasma glucose) from Life's Simple 7 metrics for CVH from the American Heart Association (AHA). Metabolic genetic risk s…