Endovascular Thrombectomy for Large-Vessel Stroke Beyond 24 Hours

Randomized clinical trial data have established the efficacy of endovascular thrombectomy for selected patients with large-vessel occlusion stroke up to 24 hours after last known well time, but whether treatment beyond 24 hours would be beneficial is unclear, since randomized trial data for this ultra-extended time window are not yet available. To explore this possibility with available observational data, researchers identified 301 adults with acute large-vessel occlusion stroke involving the internal carotid artery or M1 or M2 segments of the middle cerebral artery who had received either endovascular thrombectomy (185; 61%) or medical management (116; 39%) beyond 24 hours after symptom onset at 17 centers across the U.S., Spain, Australi…