A New Option for Patients with Chronic Limb-Threatening Ischemia?

Transcatheter arterialization of deep veins may provide benefit in cases not treatable with revascularization.

Standard care for chronic limb-threatening ischemia (CLTI) is revascularization, either by vascular surgery or catheter-based approaches, along with wound care. However, ≈20% of patients are not candidates for these therapies due to anatomic limitations.

In this industry-funded, prospective, single-group, multicenter trial, investigators evaluated outcomes of a non–FDA-approved procedure, transcatheter venous arterialization, in 105 patients (31% women; 43% Black, Hispanic, or Latino; 18% on dialysis) with CLTI involving tissue loss or gangrene and not treatable by revascularization. The procedure uses catheter-based techniques to establish a connection between a lower extremity artery (usually the popliteal artery) and an adjacent vein to a…

Reviewing Author

David J. Cohen, MD, MSc

Disclosures

Consultant/Advisory BoardMedtronic; Edwards Lifesciences; Abbott Vascular; Boston Scientific; St. Francis Hospital

Speaker’s BureauBoston Scientific; ZOLL Medical

Grant/Research SupportEdwards Lifesciences; Abbott Vascular; Boston Scientific; Corvia Medical; National Heart, Lung, and Blood Institute; Phillips, Inc.; St. Paul’s Hospital; V-Wave, Inc; ZOLL Medical; CathWorks, ANCORA

Editorial BoardsJACC; American Heart Journal; EuroIntervention; JSCAI; Structural Heart Journal

Leadership Positions in Professional SocietiesSociety of Thoracic Surgeons/American College of Cardiology TVT Registry (Co-Chair, Risk Model Development Committee); Cardiovascular Research Foundation (Co-Director, TCT Annual Meeting; Co-Director, New York Valves Annual Meeting)