CSF Findings in Patients with Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is diagnosed on the basis of clinical findings, neurophysiologic studies, and cerebrospinal fluid (CSF) examination. Albuminocytologic dissociation (ACD; high protein level but normal cell count in CSF), which is common in patients with GBS, is currently used as a diagnostic criterion, but its value has been debated and a strict definition is lacking. High CSF total protein, which is also common in patients with GBS, has been related to late performance of lumbar puncture, sensorimotor variant, and a demyelinating nerve conduction study subtype. The objective of this study was to investigate the associations of findings in CSF, electrodiagnostic subtypes, severity, and outcome in 1500 patients in the Internatio…