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The efficacy of implantable remote hemodynamic monitoring as a means of guiding pharmacotherapy in patients with heart failure (HF) remains unclear despite two previously published randomized trials, which provided inconsistent results. Current American College of Cardiology/American Heart Association HF guidelines include a weak (IIb) recommendation for consideration of remote hemodynamic monitoring in patients with HF and New York Heart Association (NYHA) class III symptoms despite optimal medical and device therapy.
The manufacturer-funded, open-label MONITOR-HF trial (NTR7672), conducted in the Netherlands, enrolled 348 individuals with NYHA class III symptoms and a previous hospitalization for HF (median age, 69 years; median left ventr…