Safety of Acute Stroke Thrombectomy in Patients with Recent Vitamin K Antagonist Use

Patients with recent VKA use and international normalized ratio >1.7 had an increased risk for brain hemorrhage compared with patients not using VKAs recently.

Patients with any of several cardiac conditions may be treated with vitamin K antagonists (VKAs), and they are at increased risk for ischemic stroke. Limited data are available on the outcomes of endovascular thrombectomy (EVT) for acute stroke treatment in patients with recent VKA use. These authors analyzed the American Heart Association Get with the Guidelines–Stroke registry, including patients enrolled between October 2015 and March 2020. They compared patients with and without VKA use in the previous 7 days. The primary endpoint was symptomatic intracranial hemorrhage (sICH), confirmed by computed tomography, within 36 hours after EVT. Secondary endpoints included life-threatening hemorrhages and mortality. The study was funded by an …

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Safety of Acute Stroke Thrombectomy in Patients with Recent Vitamin K Antagonist Use

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Reviewing Author