Safety of Thrombolysis in Patients with Intracranial Tumors and Acute Stroke

In a registry study, the rate of symptomatic brain hemorrhage was slightly higher than expected.

For patients with acute stroke, physicians consider several contraindications against intravenous thrombolysis (IVT). Some contraindications are absolute, such as presence of hemorrhage on the initial computed tomography scan, and others are relative. For patients with previously diagnosed intracranial tumors, a relative contraindication exists. However, there are few high-quality data on this topic. To evaluate in-hospital and 90-day outcomes for symptomatic and fatal intracranial hemorrhage in patients with brain tumors, these authors analyzed an international registry of patients who received IVT for acute ischemic stroke.

Among 21,289 patients in the registry, 105 patients (median age, 75; 61% women) were identified with a brain tumor. I…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Safety of Thrombolysis in Patients with Intracranial Tumors and Acute Stroke

Topics

Reviewing Author