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The term “interstitial lung abnormalities” (ILAs) is used increasingly to describe certain incidental findings on lung computed tomography (CT). In a position paper published in 2020 on this topic, ILAs were defined as incidentally identified “non-dependent abnormalities, including ground-glass or reticular abnormalities, lung distortion, traction bronchiectasis, honeycombing, and non-emphysematous cysts … involving at least 5% of a lung zone.”
To determine the prevalence of ILAs, researchers conducted this meta-analysis. Findings included the following:
In 10 studies (with 31,000 participants) of lung cancer screening with low-dose CT, overall prevalence of ILAs was 7%.
In 8 “general population” studies (with 57,000 participants), in which co…