Prognostic Value of Fractional Flow Reserve Derived from CT Angiography

Among patients with at least one 30% stenosis, FFR measurements helped predict adverse cardiac events within 3 years.

Fractional flow reserve (FFR), a measurement of blood flow across a stenotic lesion, can be derived noninvasively from coronary computed tomography angiography (CCTA). This technique is being used increasingly at many medical centers to help assess the hemodynamic significance of coronary artery stenoses. But what is the prognostic value of those measurements in predicting important outcomes such as death or myocardial infarction (MI)? In this nonrandomized cohort of Danish patients with new-onset angina who underwent CCTA and had at least one 30% stenosis, FFR measurements from CCTA (CT-FFR) were derived for the most-severe stenosis in each vessel. Patients with persistent atrial fibrillation or prior revascularization were excluded.

Among …

Reviewing Author

Kirsten E. Fleischmann, MD, MPH, FACC

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association

Kirsten E. Fleischmann, MD, MPH, FACC

Disclosures

Grant/Research SupportNational Institutes of Health

Leadership Positions in Professional SocietiesAmerican College of Cardiology/American Heart Association

Prognostic Value of Fractional Flow Reserve Derived from CT Angiography

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Reviewing Author