Presenters at the 2023 American Society of Hematology (ASH) annual meeting, held December 9–12 in San Diego, reported the latest research in hematology. NEJM Group was on hand to cover the meeting. Here, NEJM Journal Watch Oncology and Hematology reports on some of the key findings in benign hematology, and Associate Editor Dr. Anjali A. Sharathkumar provides her clinical perspective. Abstracts can be found on the ASH meeting site.
Early Data Show Sickle Hemoglobin Polymerization Inhibitor Effective, Well Tolerated
In adults with sickle cell disease (SCD), the next-generation sickle hemoglobin polymerization inhibitor known as GBT021601 is associated with large increases in mean hemoglobin (Hb) levels and is well tolerated, according to the p…
Author
DisclosuresConsultant/Advisory BoardGenentech
Grant/Research SupportX4 Pharma; Pfizer; Health Resources and Services Administration; American Thrombosis and Hemostasis Network/CDC; Carver College of Medicine
Leadership Positions in Professional SocietiesInternational Society on Thrombosis and Haemostasis (Finance Committee Member); American Society of Hematology Clinical Research Translational Institute
DisclosuresConsultant/Advisory BoardGenentech
Grant/Research SupportX4 Pharma; Pfizer; Health Resources and Services Administration; American Thrombosis and Hemostasis Network/CDC; Carver College of Medicine
Leadership Positions in Professional SocietiesInternational Society on Thrombosis and Haemostasis (Finance Committee Member); American Society of Hematology Clinical Research Translational Institute