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In recent years, pheochromocytomas are detected increasingly in patients with incidentally discovered adrenal masses, rather than in patients with classic adrenergic symptoms. This report describes 167 patients with pheochromocytoma who were evaluated and treated at a U.K. referral center between 2010 and 2022. Findings were as follows:
After excluding 20 patients whose pheochromocytomas were detected by screening (because of family history), 69% of cases were diagnosed in patients with adrenal incidentalomas, 28% in patients with adrenergic symptoms/uncontrolled hypertension, and 3% in patients with acute cardiomyopathy.
40% of patients whose pheochromocytomas were incidentalomas described adrenergic symptoms in retrospect, and 36% had known…