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In the Resynchronization–Defibrillation for Ambulatory Heart Failure Trial (RAFT; NCT00251251), use of a cardiac-resynchronization therapy defibrillator (CRT-D) significantly reduced all-cause death or hospitalization for heart failure at 5 years' follow-up compared with a standard implantable cardioverter-defibrillator (ICD) in 1798 patients with left ventricular ejection fraction (LVEF) ≤30%, QRS duration ≥120 msec, and NYAH class II or III heart failure. Now, investigators report extended follow-up results in a subset of 1050 patients.
Participants were not excluded for having right bundle-branch block, nonspecific interventricular conduction delays, right ventricular pacing, or atrial fibrillation. In the initial study, average follow-up…