Mortality Lower with Timely Reversal of Anticoagulation-Associated Intracerebral Hemorrhage

The recognition that the benefits of acute ischemic stroke interventions can be exquisitely time-dependent has led to concerted and sustained quality-improvement efforts to improve the timeliness of treatment for eligible patients. Whether a similar relationship between door-to-treatment times and outcomes can be demonstrated for reversal interventions for patients with anticoagulation-associated intracerebral hemorrhage (ICH) is unclear. To address this uncertainty, investigators used data from the American Heart Association Get With the Guidelines–Stroke quality-improvement registry to identify 9492 patients (45% female; median age, 77 years) with anticoagulation-associated ICH who had presented within 24 hours to one of 465 participating…