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The optimal antithrombotic therapy for cervical artery dissection is unclear. Two randomized trials have evaluated anticoagulation versus antiplatelet therapy: The Cervical Artery Dissection in Stroke Study (CADISS) found a nonsignificant difference between antiplatelet and anticoagulation therapy for preventing recurrent stroke, while the Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection (TREAT-CAD) trial failed to show the noninferiority of aspirin over anticoagulation. From a systematic review of the literature that identified the two randomized trials, researchers have now performed an individual patient–level meta-analysis of the data. The primary outcome was a composite of ischemic stroke, death, or major bleeding …