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Many hospitals have implemented mechanisms to prevent hospital-acquired venous thromboembolism (VTE); however, some of those protocols have led to overtreatment of low-risk patients (NEJM JW Gen Med Jul 15 2024 and J Hosp Med 2024; 19:449). Using American Society of Hematology guidelines (Blood Adv 2018; 2: 3198) and decision analysis, investigators retrospectively applied risk prediction models for both VTE risk (IMPROVE VTE risk score) and bleeding risk (IMPROVE Bleeding risk score) to 2000 hospitalized medical patients in their South Carolina healthcare system during 1 year to determine which patients merited pharmacologic VTE prophylaxis to optimize outcomes.
Providing VTE prophylaxis to patients with IMPROVE VTE scores ≥2 and IMPROVE Bl…