Managing Prosthetic Joint Infections Caused by Candida Species

In a retrospective European cohort study, treatment failure was significantly associated with implant retention compared with surgical exchange procedures.

Prosthetic joint infection (PJI) caused by Candida species is rising in frequency and difficult to treat, but high-quality evidence regarding management is lacking, and understanding of epidemiology and outcomes is limited. Researchers conducted a retrospective European cohort study including 269 patients (median age, 73) with Candida PJI at 19 hospitals in 7 countries over a 10-year period.

In all, >95% of cases involved the hip or knee. Candida albicans was the infecting organism in 56%, and C. parapsilosis in 29%. More than half of cases involved co-infection with bacteria. Debridement, antibiotics, and implant retention (DAIR) was performed in 36% of cases whereas 1- or 2-stage implant exchange procedures were done in about 29%. Triazole…

Reviewing Author

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Managing Prosthetic Joint Infections Caused by Candida Species

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Reviewing Author