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Patients often ask whether they can safely receive COVID-19 and influenza vaccines simultaneously, thus saving a second trip to the doctor's office or pharmacy. In this controlled trial, researchers evaluated 335 patients (mean age, 33) who were eligible for both vaccines. Patients were randomized to (1) receiving an mRNA COVID-19 vaccine plus a quadrivalent inactivated influenza vaccine (in opposite arms) and then receiving a placebo injection 1 to 2 weeks later or (2) receiving a COVID-19 vaccine plus a placebo injection (in opposite arms) and then receiving the influenza vaccine 1 to 2 weeks later.
At 7 days after the first administration, patients responded to questions about local or systemic side effects or vaccine reactions: ≈28% in e…