A Novel Clinical Score to Predict Late Seizures After Cerebral Venous Thrombosis

Although 1 in 10 patients with cerebral venous thrombosis (CVT) develop seizures more than 7 days after CVT diagnosis, evidence is insufficient to guide prevention and treatment of seizures in this population. These researchers aimed to develop a prognostic tool to estimate risk for post-CVT epilepsy. They developed a multivariable prediction model using data collected either prospectively or retrospectively between 1994 and 2021 from a multicenter, international, observational cohort study of 1356 adults with CVT. The authors assessed six predictors identified from prior studies: decompressive craniectomy, intracerebral hemorrhage at CVT presentation, age, seizures occurring in the acute phase, status epilepticus in the acute phase, and su…