Treatment of Restless Legs Syndrome and Periodic Limb Movement Disorder

Updated guidelines from the American Academy of Sleep downgrade the use of dopamine agonists to treat RLS.

Sponsoring Organization: American Academy of Sleep Medicine (AASM)

An expert panel from the AASM updated clinical practice guidelines for restless legs syndrome (RLS) and periodic limb movement disorder (PLMD).

Key Points

Good Practice Recommendations

Address exacerbating factors for RLS, including alcohol and caffeine use, medications (e.g., anti-histaminergic, serotonergic, and anti-dopaminergic medications), and untreated obstructive sleep apnea (OSA).
Obtain serum iron studies, including ferritin and transferrin saturation. Treat with oral or intravenous (IV) iron in adults with serum ferritin ≤75 ng/mL or transferrin saturation <20%, IV iron in adults with serum ferritin 75–100 ng/mL, and oral or IV iron in childre…

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life