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This is the first guideline from CHEST that is focused on transfusion of red blood cells (RBC) in critically ill adults, excluding those with neurological injury or trauma. It complements other guidelines from the Critical Care Societies Collaborative. In this document, a “restrictive” threshold generally means a hemoglobin level of 7 to 8 g/dL, and a “permissive” threshold generally means a level of 8.5 to 10.0 g/dL.
Use a restrictive transfusion strategy for critically ill patients, including patients with acute gastrointestinal bleeding, but excluding those with hemodynamic instability from hemorrhage (strong recommendation).
Consider a restri…