Profiles of Antimicrobial-Resistant Infections in U.S. Hospitals

From 2012 through 2022, rates of drug-resistant infections decreased among hospitalized U.S. patients, with significant variability by pathogen and region.

Drug-resistant pathogens designated as high priority by CDC and WHO include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), extended-spectrum cephalosporin-resistant Escherichia coli and Klebsiella (ESCR-EK), carbapenem-resistant Enterobacterales (CRE), carbapenem-resistant Acinetobacter (CRAsp), and multidrug-resistant Pseudomonas aeruginosa (MDR P. aeruginosa). In a retrospective analysis of U.S. data from hospitals and clinical cultures, investigators assessed temporal trends in incidence of infections with high-priority pathogens in hospitalized patients from 2012 through 2022. Community-onset infections were defined as those occurring before day 4 of hospitalization; hospital-onset infection…

Reviewing Author

Hana M. El Sahly, MD

Disclosures

Grant/Research SupportNational Institutes of Health

Hana M. El Sahly, MD

Disclosures

Grant/Research SupportNational Institutes of Health

Profiles of Antimicrobial-Resistant Infections in U.S. Hospitals

Topics

Reviewing Author