In an ambulatory cohort with mild-to-moderate symptoms, advising daily fluid restriction provided no benefit.
The evidence to support fluid restriction in the management of heart failure (HF) is thin, however intuitively appealing the practice might seem. In this randomized, open-label trial, researchers assessed the effect of recommending fluid restriction in chronic ambulatory HF.
The 504 study participants had chronic HF for at least 6 months and no recent HF hospitalization or cardiovascular procedures. Most were men (67%) with mild-to-moderate HF symptoms (New York Heart Association class II symptoms, 87%); half had reduced ejection fraction. They were randomized to receive lifestyle advice recommending either fluid restriction (<1.5 L/day) or liberal fluid intake (no maximum).
After 3 months of follow-up, the fluid-restriction group self-report…
Reviewing Author
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)
DisclosuresConsultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research
Grant/Research SupportNational Heart, Lung, and Blood Institute
Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)
Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)