Comparing Supplemental Imaging Modalities in Women with Dense Breasts

In a randomized trial, MRI and contrast-enhanced mammography detected more cancers than did ultrasound.

Screening mammography has lower sensitivity among women with dense breast, but data on supplemental imaging techniques are limited. In this U.K.-based trial, researchers evaluated cancer detection in 6300 middle-aged women (age range, 50–70), who had heterogeneously or extremely dense breasts and negative baseline mammography findings. Participants were randomized to receive one of the following: Abbreviated contrast-enhanced magnetic resonance imaging (MRI); automated whole-breast ultrasound (ABUS), which uses an automated, rather than hand-held, transducer; or iodinated contrast-enhanced mammography.

Cancer-detection rates were 17, 4, and 19 per 1000 women who received MRI, ABUS, and contrast-enhanced mammography, respectively. In contrast…

Reviewing Author

Sarah E. Post, MD

Disclosures

Nothing to disclose

Sarah E. Post, MD

Disclosures

Nothing to disclose

Comparing Supplemental Imaging Modalities in Women with Dense Breasts

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Reviewing Author