A New Bariatric Surgical Option: Single-Anastomosis Duodeno-Ileal Bypass

In a randomized trial, this technique compared favorably with Roux-en-Y gastric bypass through 2 years of follow-up.

First described in 2007, single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is a simplified bariatric surgical technique that has a substantial theoretical advantage over traditional Roux-en-Y bypass (RYGB): one anastomosis instead of two. Now, for the first time, researchers in France compared these procedures head-to-head in a randomized trial that involved 380 patients with obesity.

Patients' mean body-mass index was 46 kg/m², and they had either no previous bariatric surgery or suboptimal weight loss after sleeve gastrectomy. At 2 years, key outcomes were as follows:

The SADI-S group had significantly greater weight loss than the RYGB group as defined by a formula based on ideal body weight.
Early surgical complicatio…

Reviewing Author

Nolan J. Mischel, MD

Disclosures

Nothing to disclose

Nolan J. Mischel, MD

Disclosures

Nothing to disclose

A New Bariatric Surgical Option: Single-Anastomosis Duodeno-Ileal Bypass

Topics

Reviewing Author