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The recent epidemic of methamphetamine abuse in the U.S. has been associated with an increase in unprotected sex and possibly HIV infection, primarily among men who have sex with men (MSM). In this study, investigators evaluated amphetamine use and HIV incidence among MSM who sought anonymous HIV testing in San Francisco in 2001 and 2002. Information on drug use and sexual behavior was obtained prior to testing, and annual HIV incidence was estimated using the Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS). Injection drug users were excluded from analysis, leaving 2991 MSM in the study (median age, 34; 71% white).
In the year prior to testing, 52% of study participants had unprotected sex, 40% had 10 or more sexual partne…