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The rate of infections caused by community-acquired methicillin-resistant Staphylococcus aureus (MRSA) has been increasing dramatically, but the role of antibiotics for treatment remains ill-defined. In this retrospective study, investigators identified all patients with a positive culture for S. aureus (SA) between 1998 and 2005 at a Boston clinic. To be included in the analysis, patients had to have SA isolated from a nonwound site or clinical evidence of a skin or soft-tissue infection (SSTI) with SA isolated from a wound culture.
A total of 164 patients were found to be infected with MRSA and 160 with methicillin-sensitive SA (MSSA). The groups were similar with respect to age, sex, and race. A significantly higher percentage of MRSA pat…