Dual Infection with HBV and HCV in HIV-Positive Patients

In HIV-infected patients who are also infected with HBV and HCV, treatment for one type of viral hepatitis does not appear to cause rebound of the other.

Because of shared routes of transmission, dual infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is sometimes seen in HIV-positive patients. Development of these two types of viral hepatitis can result in liver disease that is more severe than that caused by either virus alone. In HIV-negative patients, HBV and HCV appear to inhibit each other reciprocally; that is, replication of one type of virus appears to predominate over the other, perhaps because of viral interference. If this reciprocal interaction occurs in HIV-positive patients and one hepatitis virus holds the other in check, does treatment for one type result in rebound of the other?

Investigators in Spain identified 21 HIV-infected patients who were positive for …

Reviewing Author

Rajesh T. Gandhi, MD

Dual Infection with HBV and HCV in HIV-Positive Patients

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Reviewing Author