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As patients with HIV infection live longer, their potential risk for cardiovascular disease becomes increasingly important. Although several studies have described an association between antiretroviral therapy and risk for myocardial infarction (MI), few data are available on the extent to which HIV infection influences MI risk.
In the largest study to date on this topic, investigators used a data registry from two large Boston hospitals to compare MI rates between 3851 HIV-infected patients and more than 1 million patients without HIV diagnoses. ICD-9 codes were used to identify cases of MI, as well as cardiovascular risk factors, including hypertension, diabetes, and dyslipidemia. Data on smoking were available for only a small subset of p…