The Predictive Value of Rapid Virologic Response to HCV Therapy in Coinfected Patients

Retrospective data indicate that, in coinfected patients, rapid virologic response to HCV therapy might predict sustained virologic response.

In patients with hepatitis C virus (HCV) monoinfection, a rapid virologic response (RVR) to HCV treatment increases the likelihood of a sustained virologic response (SVR) 6 months after completion of therapy. Although preliminary data suggest that RVR might also predict SVR in HIV-coinfected patients (ACC Jul 9 2007), definitive data from prospective trials are lacking.

In the present (retrospective) study, investigators reviewed data from 258 HIV/HCV-coinfected patients in Spain who received pegylated interferon and ribavirin. Of these patients, 101 were eligible for analysis based on the following criteria: They had HCV RNA levels measured at week 4 of treatment, they had received an optimum dosage of treatment, and they had either complet…

Reviewing Author

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

The Predictive Value of Rapid Virologic Response to HCV Therapy in Coinfected Patients

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Reviewing Author