Heart Disease Risk in HIV-Positive Men and Women

Data from two large U.S. cohorts link PI use, obesity, and low income with increased risk for coronary heart disease.

Improvements in long-term prognosis as a result of potent combination antiretroviral therapy (ART) have led to a shift in the clinical burden of HIV disease — from traditional AIDS-defining conditions to more-standard health problems, such as coronary heart disease (CHD; ACC Jul 30 2007). In the present analysis, investigators estimated the 10-year predicted risk for CHD among individuals participating in either the Multicenter AIDS Cohort Study (931 HIV-positive and 1099 HIV-negative men) or the Women’s Interagency HIV Study (1455 HIV-positive and 576 HIV-negative women). Predicted absolute risk was calculated using Framingham cardiovascular risk equations and then classified as low (<15%), moderate (15%–25%), or high (>25%). Those with di…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Heart Disease Risk in HIV-Positive Men and Women

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Reviewing Author