Non–AIDS-Defining Cancer in HIV-Infected Patients

In a large urban cohort, non–AIDS-defining cancers have become more common than AIDS-defining ones.

Since the widespread introduction of potent antiretroviral therapy (ART), the burden of cancer in the HIV-infected population has shifted away from AIDS-defining malignancies (most of which are related to immunosuppression) toward more non–AIDS-defining cancers. In this retrospective analysis, investigators studied the incidence and outcomes of both types of malignancies in the current HIV-treatment era. The study involved 2566 patients who were enrolled in the Johns Hopkins HIV cohort.

From 1996 through 2005, 138 cases of AIDS-defining cancer occurred in the cohort. During this period, the incidence of these cancers decreased significantly (from 12.5 to 3.5 cases per 1000 person-years), largely because of a dramatic drop in new cases of Kap…

Reviewing Author

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Non–AIDS-Defining Cancer in HIV-Infected Patients

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Reviewing Author