Low Rate of Vertical HIV Transmission in the U.K. and Ireland

Only three cases of transmission occurred among 2117 infants whose mothers achieved undetectable viral loads in response to ART.

Successful prevention of vertical HIV transmission hinges on the mother receiving antiretroviral therapy (ART). In this study, which was previously reported at the 15th Retrovirus Conference (AIDS Clin Care Mar 10 2008), researchers described the experience of more than 5000 women who received antiretrovirals during pregnancy between 2000 and 2006 in the U.K. and Ireland.

The overall rate of vertical transmission was 1.2% (61 of 5151). Rates were even lower in certain circumstances: 0.7% (17 of 2286) with combination ART and planned cesarean delivery, 0.7% (4 of 559) with combination ART and planned vaginal delivery, and 0% (0 of 464) with AZT monotherapy and planned cesarean delivery. Only three transmissions occurred (0.1%) among the 2117 …

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Low Rate of Vertical HIV Transmission in the U.K. and Ireland

Topics

Reviewing Author