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Dear Readers:
Periodically in AIDS Clinical Care, we publish a case in the “Antiretroviral Rounds” column and ask clinical experts how they would manage such a patient. Now, we’ve created an online forum where readers can share their perspectives and, in most cases, learn how these patients were actually managed.
Many of you have already responded to the recent case in which a patient with mostly undetectable viral loads had triple-class resistance detected during a transient virologic rebound due to pancreatitis. Like our experts, you were split on whether to change the patient’s regimen, but most opted not to. As the treating clinician in that particular case, I did recommend a regimen change. For details about the outcome and to review a selection of reader responses, please visit our online discussion.
We have also posted our latest case online — a patient who requested the “one-pill treatment” but has documented resistance to FTC with the M184V mutation. Feel free to weigh in, and then we’ll describe how this case was actually handled and reveal the outcome.