Diminished CD4-Cell Recovery in Older Patients Despite Good Adherence

A small retrospective study highlights the importance of detecting HIV early in older individuals.

The number of older adults with HIV infection is steadily increasing, partly because of improved long-term survival with antiretroviral therapy (ART) but also because increasing numbers of older people are engaging in high-risk behaviors. To better understand the treatment responses of older HIV-infected patients, investigators reviewed the medical records of 112 patients in Madrid, Spain, who were 55 or older at the time of ART initiation. Eighty-two were aged 55 to 64 (mean age, 58; median CD4 count, 266 cells/mm³), and 30 were 65 or older (mean age, 70; median CD4 count, 186 cells/mm³). Median follow-up was 41 months.

By month 6 of ART, more than 60% of patients had achieved undetectable viral loads on a variety of ART regimens. Rates of …

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Diminished CD4-Cell Recovery in Older Patients Despite Good Adherence

Topics

Reviewing Author