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Low bone-mineral density (BMD) is one of the more commonly observed noninfectious problems in HIV clinical practice. However, risk factors and management strategies are poorly understood. To address this gap, researchers evaluated data collected as part of a prospective cohort study of nutritional and metabolic issues among HIV-infected patients.
The study took place from mid-1996 through mid-2003 and included 283 men, 76 premenopausal women, and 20 postmenopausal women. Dual-energy x-ray absorptiometry (DXA) scans were performed annually. Diet, HIV-related clinical events, antiretroviral therapy use, and steroid use were assessed semiannually.
At baseline, BMD was substantially lower for white men than for black men and, regardless of race, …