Loading...
The decline in opportunistic infections since the introduction of potent antiretroviral therapy (ART) has been so dramatic that infectious-complication rates often are assumed to be similar between HIV-negative and HIV-positive individuals, provided that the latter are effectively treated and have normal or near-normal CD4-cell counts. However, a recent study from Denmark challenges this assumption.
Investigators compared rates of first pneumonia-related hospitalizations between 3516 HIV-infected people in the Danish HIV Cohort Study and 328,738 population-based controls (matched for sex, age, and municipality). Hospitalizations due to Pneumocystis jirovecii pneumonia were excluded from analysis. The study period, from 1995 through 2007, was…