HPV Infection in HIV-Positive MSM

Infections with human papillomavirus types 16 and 18, which confer high risk for anal cancer, are acquired at high rates among MSM and are slow to clear.

Despite the widespread use of potent antiretroviral therapy (ART), the incidence of anal cancer has continued to increase among HIV-infected men who have sex with men (MSM). Anal cancer is preceded by infection with oncogenic genotypes of human papillomavirus (HPV) and the development of anal intraepithelial neoplasia (AIN). To better understand the acquisition and clearance of anal HPV infection among HIV-infected MSM, investigators initiated the HIPVIRG study in Montreal.

This longitudinal cohort study involved 247 HIV-infected MSM (age range, 18–65; 93% ART experienced). Anal samples were collected for HPV testing and cytology at baseline and then every 6 months for 3 years. High-resolution anoscopy was done annually or — if high-grade AI…

Reviewing Author

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

HPV Infection in HIV-Positive MSM

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Reviewing Author