The guidelines include new background information but no new clinical recommendations.
On April 29, 2009, the U.S. Public Health Service released updated guidelines for the use of antiretroviral agents in HIV-infected pregnant women and in infants. None of the panel’s clinical recommendations have changed substantially. However, the guidelines do provide helpful new background information, including:
Data from recent trials of antiretrovirals to prevent transmission of HIV through breast-feeding
More detail on the recommended duration of AZT prophylaxis in infants
Results from carcinogenicity and teratogenicity studies in animals
Information on etravirine
A supplement on the safety and toxicity of individual antiretrovirals in pregnancy
Citation(s):
Perinatal HIV Guidelines Working Group. Public Health Service Task Force recommendat…