An analysis of PEPFAR’s effectiveness in 12 African countries reveals a significant decrease in the number of HIV-related deaths, but not in HIV prevalence.
Since its inception in 2003, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) has provided funding for HIV and AIDS prevention, treatment, and care to 15 focus countries, 12 of which are in sub-Saharan Africa. Now, in the first quantitative analysis of the program’s success, researchers have used data from the Joint United Nations Programme on HIV/AIDS to determine the epidemiology of AIDS and HIV infection in 41 sub-Saharan African countries (the 12 PEPFAR focus countries and 29 control countries) with a generalized HIV epidemic, defined as HIV prevalence in antenatal clinics >1% and predominantly heterosexual transmission.
The researchers examined three outcomes (HIV prevalence among adults aged 15–49, number of HIV-related dea…
Reviewing Author
DisclosuresConsultant/Advisory BoardUNAIDS; WHO; Bill and Melinda Gates Foundation, Population Council
Grant/Research SupportNIH; National Institute of Allergy and Infectious Diseases; Tides Foundation/MAC AIDS Fund; USAID; South African National Research Foundation; European Union; South African Medical Research Council
Editorial BoardsNew England Journal of Medicine; AIDS Reviews; AIDS Research and Human Retroviruses; mBio; Indian Journal of Medical Research; JAIDS: Journal of Acquired Immune Deficiency Syndromes
DisclosuresConsultant/Advisory BoardUNAIDS; WHO; Bill and Melinda Gates Foundation, Population Council
Grant/Research SupportNIH; National Institute of Allergy and Infectious Diseases; Tides Foundation/MAC AIDS Fund; USAID; South African National Research Foundation; European Union; South African Medical Research Council
Editorial BoardsNew England Journal of Medicine; AIDS Reviews; AIDS Research and Human Retroviruses; mBio; Indian Journal of Medical Research; JAIDS: Journal of Acquired Immune Deficiency Syndromes