Can the Diagnosis and Assessment of HIV-Associated Sensory Neuropathy Be Simplified?

The combination of cooling detection, tendon reflexes, and pin-stick sensitivity was found to be sufficient for diagnosing HIV-associated sensory neuropathy.

Peripheral sensory neuropathy (both HIV-related and drug-related) remains common in the era of potent antiretroviral therapy. Diagnosis of distal sensory polyneuropathy (DSP) can be challenging and often requires considerable time, expertise, and the use of expensive and even invasive tests. In this study from the AIDS Clinical Trials Group, investigators evaluated whether DSP could be diagnosed as reliably with a subset of relatively simple tests as with tests that are more time-consuming (such as quantitative sensory tests) or invasive (such as nerve conduction studies and assessment of epidermal nerve fiber density).

A total of 101 HIV-infected adults (90% men; 60% white; median age, 45; median baseline CD4 count, 169 cells/mm³; median ba…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Can the Diagnosis and Assessment of HIV-Associated Sensory Neuropathy Be Simplified?

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Reviewing Author