Liver Transplantation in HIV-Infected Patients

Survival rates were 85% at 1 year and 64% at 5 years. The vast majority of patients were able to maintain HIV control following transplantation.

End-stage liver disease from hepatitis C virus (HCV) infection is an increasing cause of morbidity and mortality among HIV-infected patients. Liver transplantation has been shown to be effective in this population (Am J Transplant 2008; 8:355), but concerns persist regarding patient and graft survival rates and also the possible loss of HIV control because of drug–drug interactions.

Now, investigators have conducted a meta-analysis of 15 observational studies and 49 case reports, describing 902 HIV-infected patients who underwent liver transplantation in the current HIV treatment era. Most of the studies were conducted in Europe (45) or the U.S. (15).

Patient survival estimates (based on the observational studies) were 84.5% at 1 year, 66.2% …

Reviewing Author

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Sonia Nagy Chimienti, MD

Disclosures

Nothing to disclose

Liver Transplantation in HIV-Infected Patients

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Reviewing Author