HIV Replication and Immune Status Linked to MI Risk Among HIV-Infected People

These associations were seen independent of traditional cardiovascular risk factors and the effects of antiretroviral therapy.

HIV-infected patients have a higher prevalence of cardiovascular disease, including myocardial infarction (MI), than the general population, but the factors underlying this excess risk are still being evaluated. Traditional cardiovascular risk factors, exposure to certain antiretrovirals, and ongoing HIV replication have all been found to be important. In this nested case-control study, researchers examined the role of virologic and immunologic parameters on MI risk using the French Hospital Database.

The investigators identified 289 HIV-infected patients who had a first MI reported between 2000 and 2006 (case patients) and matched them with 884 HIV-infected patients without MI (controls). The case patients were found to have a higher preval…

Reviewing Author

Carlos del Rio, MD

HIV Replication and Immune Status Linked to MI Risk Among HIV-Infected People

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Reviewing Author