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An overview of KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
In 2025, the international group KDIGO (Kidney Disease: Improving Global Outcomes) published a guideline on management of autosomal-dominant polycystic kidney disease (ADPKD). Now, a working group from the Kidney Disease Outcomes Quality Initiative (KDOQI) has reviewed the 2025 KDIGO guideline and has published helpful point-by-point commentary.
ADPKD often is discovered incidentally during imaging, and imaging remains central to diagnosis, with ultrasound as the best imaging modality for screening.
Genetic testing is integral to diagnosis as i…